Gene interactions and pathways from curated databases and text-mining

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CXCL2 — IL10

Text-mined interactions from Literome

Wright et al., Microbes Infect 2004 : IL-10 and IL-13 reduced S. aureus induced osteoblast C-X-C chemokine secretion, whereas IL-4 decreased CXCL8 secretion 2.5-fold and increased CXCL10 secretion 3-fold ( all P < 0.05 )
Rossato et al., Eur J Immunol 2007 : We also show that IL-10 induced transcriptional repression of TNF-alpha and CXCL8 genes consists of two distinct phases : an early one, occurring rapidly and in a protein synthesis independent manner, followed by a second phase, more delayed and dependent on protein synthesis
Tamassia et al., Int Immunol 2008 (Sepsis...) : Consistent with the presence of a fully functional IL-10R, modulation of LPS induced CXCL8 , CCL4, tumour necrosis factor-alpha and IL-1ra gene expression was also rapidly induced by IL-10 in septic, but not normal, neutrophils