Gene interactions and pathways from curated databases and text-mining

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BCL6 — IL11

Text-mined interactions from Literome

He et al., J Clin Invest 2005 (Lung Diseases...) : In contrast, IL-11 stimulated A1, diminished the toxic effects of hyperoxia, stimulated Bcl-2 and Bcl-xl , and enhanced murine survival in 100 % O ( 2 ) ... In A1-null mice, IL-11 induced protection, survival advantage, and Bcl-2 and Bcl-xl induction were significantly decreased
Nakayamada et al., Immunity 2011 : Herein, we showed interleukin-12 acting via the transcription factor STAT4 induced both Il21 and Bcl6 genes, generating cells with features of both Tfh and Th1 cells