Gene interactions and pathways from curated databases and text-mining

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CXCL2 — IL4

Text-mined interactions from Literome

Thomas et al., J Immunol 2004 (Bronchial Hyperreactivity) : In lymphocytes restimulated with CXCL9 and allergen in vitro, CXCL9 down-regulated IL-4 expression and up-regulated IFN-gamma expression, suggesting that CXCL9 is able to direct activated lymphocytes toward a Th1-type phenotype
Méndez-Samperio et al., Mediators Inflamm 2006 : We found that, although M. bovis BCG induced gene expression of CXCL-8 and CXCL-10 in M. bovis BCG infected human epithelial cells, CXCL-8 mRNA level was significantly reduced by IL-4 , whereas no significant effect of IL-4 was observed on CXCL10 mRNA level ... Furthermore, we found a similar effect of IL-4 on M. bovis BCG induced CXCL-8 and CXCL-10 secretion by using other human epithelial A549 cell line
Huang et al., Am J Physiol Lung Cell Mol Physiol 2007 : IL-4 stimulates the expression of CXCL-8 , E-selectin, VEGF, and inducible nitric oxide synthase mRNA by equine pulmonary artery endothelial cells