Gene interactions and pathways from curated databases and text-mining

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IL5 — RAD50

Text-mined interactions from Literome

Yamada et al., Anticancer Res 2002 (Stomach Neoplasms) : TRF1, TRF2 and TIN2 are negative regulators of telomere length, while tankyrase and Rap1 act as positive regulators
Wu et al., Nature structural & molecular biology 2007 : We propose that MRN is required for TRF1 phosphorylation by ATM and that such phosphorylation results in the release of TRF1 from telomeres, promoting telomerase access to the ends of telomeres