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IL6 — POLDIP2

Text-mined interactions from Literome

Eliopoulos et al., J Biol Chem 1999 : In addition, we have found that p38 inhibition significantly impaired LMP1 mediated interleukin-6 and -8 expression
Hayashi et al., Eur Respir J 2000 : This study investigated the role of the extracellular signal regulated protein kinase 1/2 ( ERK 1/2 ) and p38 mitogen activated protein kinase ( p38 MAPK ) in the BK-induced interleukin (IL)-6 and IL-8 production by human lung fibroblasts
Patil et al., Immunol Invest 2004 : Endogenous IL-6 and reporter gene eGFP-IL-6 3'UTR mRNA was regulated by p38 in MC6 cells
Kotani et al., Eur Respir J 2004 (Disease Models, Animal...) : Physiological parameters, tumour necrosis factor (TNF)-alpha, interleukin (IL)-8 and activation of mitogen activated protein kinases ( extracellular signal regulated kinase ( ERK ) 1/2, p38 and stress activated protein kinase ( SAPK ) / c-Jun N-terminal kinase (JNK) ) were measured
Wong et al., Am J Respir Cell Mol Biol 2005 : Interleukin-25 induced chemokines and interleukin-6 release from eosinophils is mediated by p38 mitogen activated protein kinase, c-Jun N-terminal kinase, and nuclear factor-kappaB
Chang et al., Am J Physiol Lung Cell Mol Physiol 2005 (Carcinoma, Non-Small-Cell Lung...) : SB-203580, a p38 MAPK-specific inhibitor, inhibits IL-6 induced p38 MAPK phosphorylating activity and suppresses IL-6 stimulated cell proliferation
Nonn et al., Cancer Res 2006 (Prostatic Neoplasms) : Inhibition of p38 by vitamin D reduces interleukin-6 production in normal prostate cells via mitogen activated protein kinase phosphatase 5 : implications for prostate cancer prevention by vitamin D
Kang et al., Eur J Pharmacol 2008 : We found that a p38 inhibitor ( SB203580 ) and an ERK 1/2 inhibitor ( PD98059 ) significantly affected LPS induced IL-6 production
Moutzouris et al., Biochim Biophys Acta 2010 (Asthma) : Investigating the effect of MG-132 on secretion of the cytokine IL-6 we show that while short-term pretreatment with MG-132 ( 30min ) partially reduced TNFalpha induced IL-6 via inhibition of IkappaB-alpha degradation and the NF-kappaB pathway, longer-term proteasome inhibition ( up to 24h ) robustly upregulated MKP-1 and was temporally correlated with repression of p38 mediated IL-6 secretion from ASM cells
Weber et al., Science signaling 2010 : In response to ligand binding of the receptor, a complex sequence of combinatorial phosphorylation and ubiquitination events results in activation of nuclear factor kappaB signaling and the JNK and p38 mitogen activated protein kinase pathways, which, cooperatively, induce the expression of canonical IL-1 target genes ( such as IL-6 , IL-8, MCP-1, COX-2, IkappaBalpha, IL-1alpha, IL-1beta, MKP-1 ) by transcriptional and posttranscriptional mechanisms
Nieminen et al., Arthritis Rheum 2010 : Aurothiomalate inhibits cyclooxygenase 2, matrix metalloproteinase 3, and interleukin-6 expression in chondrocytes by increasing MAPK phosphatase 1 expression and decreasing p38 phosphorylation : MAPK phosphatase 1 as a novel target for antirheumatic drugs
Ryll et al., Molecular bioSystems 2011 (MAP Kinase Signaling System) : Our model based data analysis, for instance, suggested model modifications regarding ( i ) Akt contribution to IL-1 stimulated p38 MAPK activation and ( ii ) insignificant p38 MAPK activation in response to IL-6
El Hajj et al., Endocrinology 2012 (Inflammation) : Furthermore, expression of IL-6 and IL-8 cytokines in patient fibroblasts was down-regulated by MAPK, p38MAPK , and Jun N-terminal kinase inhibitors