Gene interactions and pathways from curated databases and text-mining

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IRAK2 — MAPK6

Text-mined interactions from Literome

Conner et al., J Exp Med 2009 : In the MOLF/Ei TLR signaling network, IRAK-2 promotes early nuclear factor kappaB (NF-kappaB) activity and is essential for the activation of p38 MAPK ... In the MOLF/Ei TLR signaling network, IRAK-2 promotes early nuclear factor kappaB (NF-kappaB) activity and is essential for the activation of p38 MAPK
Yin et al., J Interferon Cytokine Res 2011 : Taken together, these results suggest that the kinase activity of IRAK2 is required for the optimal activation of mitogen activated protein kinase signaling, which regulates cytokine and chemokine production at posttranscriptional levels
Dauphinee et al., Am J Physiol Heart Circ Physiol 2011 : We find that Ga ( i/o ) -mediated activation of the MAPK is independent of the canonical MyD88, interleukin-1 receptor associated kinase , and tumor necrosis factor receptor associated factor 6 signaling cascade in LPS stimulated cells