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CXCL1 — ITGAM

Text-mined interactions from Literome

Casilli et al., Biochem Pharmacol 2005 : Our results show that repertaxin potently and selectively blocked PMN adhesion to fibrinogen and CD11b up-regulation induced by CXCL8
Detmers et al., J Immunol 1991 : NAP-2, melanoma growth stimulatory activity , and two forms of NAP-1/IL-8 ( ser-NAP-1/IL-8 and ala-NAP-1/IL-8, consisting of 72 and 77 amino acids, respectively ), each caused an increase in the expression of CD11b/CD18 ( CR3 ) and CR1, which was accompanied by a decrease in the expression of leukocyte adhesion molecule-1 ( LAM-1, LECAM-1 )
Lazaar et al., Br J Clin Pharmacol 2011 (Bronchitis) : Flow cytometric determination of ex vivo CXCL1 induced CD11b expression on peripheral blood neutrophils was performed following single dose oral administration of SB-656933 ( dose range 2-1100 mg ) ... Oral administration of SB-656933 resulted in significant inhibition of CXCL1 induced CD11b expression on peripheral blood neutrophils at single doses greater than or equal to 50 mg. Maximum inhibition ( 70 % ) relative to placebo was observed following administration of SB-656933 400 mg ( 95 % CI 60 %, 77 % )