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CD40LG — JAG1
Text-mined interactions from Literome
Kalled et al., J Immunol 2001
(Lupus Nephritis) :
We suggest that these mechanisms comprise an autostimulatory loop, maintaining the cascade of autoimmunity by DC presentation of
self-Ags derived from apoptotic cells and
CD154 mediated
costimulation
Commandeur et al., J Immunol 2013
(Disease Models, Animal...) :
Finally, IVE-TB
Ags induced strong IFN-? ( + ) /TNF-a ( + ) CD8 ( + ) and TNF-a ( + ) /IL-2 ( + )
CD154 ( + ) /CD4 ( + ) T cell responses in PBMC from long-term latently M. tuberculosis infected individuals
Ozaki et al., J Immunol 1997
:
Whereas the response to splenic APC expressing Mls(a)
Ags requires
CD40L expression, the response to alloantigen bearing APC does not