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KMT2D — TP53

Text-mined interactions from Literome

Lee et al., Proc Natl Acad Sci U S A 2009 (Cell Transformation, Neoplastic...) : Consistent with the in vivo observations, and the demonstration of a direct interaction between p53 and ASCOM, cell based assays have revealed that ASCOM , through ASC-2 and MLL3/4, acts as a p53 coactivator and is required for H3K4-trimethyation and expression of endogenous p53-target genes in response to the DNA damaging agent doxorubicin
Li et al., Mol Cell 2009 : We further demonstrate that MOF-MSL1v1 is specifically required for optimal transcription activation of p53 target genes both in vitro and in vivo