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EPHB2 — LRP2

Text-mined interactions from Literome

Webb et al., J Cell Sci 2000 (Fibrosarcoma...) : By regulating the uPA/uPAR system, LRP may also regulate ERK activation, cellular migration, and invasion
Ma et al., J Cell Biol 2002 : In addition to Rac1, LRP-1 suppressed activation of extracellular signal regulated kinase ( ERK ) in MEFs ; however, it was Rac1 ( and not ERK ) that was responsible for the effects of LRP-1 on MEF migration ... Thus, LRP-1 regulates two signaling proteins in the same cell ( Rac1 and ERK ), both of which may impact on cell migration
Hosojima et al., Endocrinology 2009 : The AT(1A)R mediated decrease in megalin expression was partially prevented by ERK inhibitors ... Collectively the AT(1A)R mediated ERK signaling is involved in suppressing megalin expression in the OK cell line, and insulin competes with this pathway