Gene interactions and pathways from curated databases and text-mining

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LRP8 — RELA

Text-mined interactions from Literome

Yu et al., Blood 2005 (Arteriosclerosis) : Endothelial expression of E-selectin is induced by the platelet-specific chemokine platelet factor 4 through LRP in an NF-kappaB dependent manner
Zhang et al., Am J Pathol 2007 (Brain Ischemia...) : In conclusion, our results demonstrate that after MCAO the interaction between tPA and LRP results in NF-kappaB activation in astrocytes and induction of inducible nitric-oxide synthase expression in the ischemic tissue, suggesting a cytokine-like plasminogen independent role for tPA during cerebral ischemia