Gene interactions and pathways from curated databases and text-mining

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CXCL2 — LTA

Text-mined interactions from Literome

Staquet et al., J Dent Res 2008 : CXCL2 and CXCL10 were thus increased by LTA only in odontoblast-like cells, while LPS increased CCL7, CCL26, and CXCL11 only in fibroblasts
Sawa et al., Cell Tissue Res 2008 : The expression of CCL2, CCL5, and CCL20 ( Cys-Cys motif chemokines ) and of CXCL1, CXCL3, CXCL5, CXCL6, and CXCL8 ( Cys-X-Cys motif chemokines ) was induced in LEC with LTA
Stich et al., Res Vet Sci 2011 : Lipopolysaccharide was a more potent inducer of IL-1ß and CXCL-8 than LTA or PG and LTA is a more potent inducer of CXCL-8 than PG. Based on these data, PAMPs from gram positive and negative bacteria induce TNF, IL-1ß and CXCL-8 production in feline whole blood
Fargues et al., Bull Group Int Rech Sci Stomatol Odontol 2010 : We provide here additional data showing the fine localization of NOD2 in healthy dental pulps, as well as differential regulation of TLR2, TLR4, NOD2, CCL2 and CXCL8 genes by LTA and the synthetic TLR2 agonists Pam2CSK4 and Pam3CSK4