Gene interactions and pathways from curated databases and text-mining

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MAPK12 — WNK1

Text-mined interactions from Literome

Rahman et al., Am J Physiol Lung Cell Mol Physiol 2004 : Because p38 MAPK can induce transcriptional activity of RelA/p65 without altering the DNA binding function of NF-kappaB, we addressed the possibility that cAMP antagonizes thrombin induced NF-kappaB activity and ICAM-1 expression by preventing the activation of p38 MAPK
Syeda et al., J Biol Chem 2006 : Activation of PAR-1 or PAR-2 promoted nuclear translocation and phosphorylation of p65-NF-kappaB , and thrombin induced but not PAR-2 induced p65-NF-kappaB phosphorylation was reduced by inhibition of MEK or p38MAPK
Kim et al., Microbes Infect 2006 (Fibrosarcoma...) : In addition, although phosphorylation of NF-kappaB p65 in spleen was equally enhanced in the ATCC27139- and the ATCC27139-J1R treated groups, phosphorylation of both p38 MAPK and MAPKAPK-2 was significantly induced only by ATCC27139
El-Bikai et al., Arthritis Res Ther 2010 (Osteoarthritis) : It inhibited a1ß1 integrin and Col II expression as well as ERK1/2 and NF-?B-p65 phosphorylation, but, in contrast, markedly elicited PGE2 release, COX-2 expression and p38 MAPK phosphorylation