Gene interactions and pathways from curated databases and text-mining

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MAPK14 — SRPK1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Hayes et al., Cancer Res 2007 (Breast Neoplasms...) : Consequently, we have shown that targeted inhibition of SRPK1 in tumor cells results in reduced phosphorylation of MAPK3, MAPK1 , and AKT
Odunsi et al., PloS one 2012 (Carcinoma...) : Reduction of SRPK1 expression using small interfering RNA ( siRNA ) encoding small hairpin RNA in ovarian cancer cells led to ( i ) reduced cell proliferation rate, slower cell cycle progression and compromised anchorage independent growth and migration ability in vitro, ( ii ) decreased level of phosphorylation of multiple serine-arginine proteins, and P44/42MAPK and AKT proteins, and ( iii ) enhanced sensitivity to cisplatin