Gene interactions and pathways from curated databases and text-mining

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MDM2 — MET

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: MDM2 → MET (increases) Moumen et al., Development 2007
    Evidence: We also demonstrate that the PI3K effector Akt is required for Met-triggered Mdm2 upregulation, in addition to being necessary for the nuclear translocation of Mdm2.
  • KEGG Endocytosis: CBL/CBLB/CBLC/ITCH/MDM2/NEDD4/NEDD4L/RNF41/SMURF1/SMURF2/TRAF6/WWP1 → CSF1R/EGFR/ERBB3/ERBB4/FGFR2/FGFR3/FGFR4/FLT1/IGF1R/KDR/KIT/MET/NTRK1/PDGFRA/RET (protein-protein, ubiquination)