Gene interactions and pathways from curated databases and text-mining

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CXCL2 — MMP2

Text-mined interactions from Literome

Hu et al., Cancer Sci 2008 (Neoplasm Invasiveness...) : Furthermore, in contrast to CXCL12, which enhanced the activity of matrix metalloproteinase (MMP) 9 and MMP2 in PC3 and LNCap, CXCL16 ligation resulted in stronger MMP9 and MMP2 activity in LNCap but not in PC3
Jovanović et al., Reproduction 2010 : Exogenous IL8/CXCL8 increased trophoblast cell migration and invasion, which may be partly attributable to stimulation of MMP2 and MMP9 levels and an increase in integrins
Laird et al., Hum Reprod 2011 : In contrast to its effects in other cells, CXCL12 had no effect on MMP-2 or MMP-9 production by endometrial stromal or epithelial cells
Takekoshi et al., Mol Cancer Ther 2012 (Lung Neoplasms...) : In vitro analysis of amino-terminal cleavage by enzymes dipeptidylpeptidase IV ( DPPIV/CD26 ) and matrix metalloproteinase-2 (MMP-2) resulted in 25-fold and 2-fold slower degradation rates, respectively, of CXCL122 compared with wtCXCL12
Zhang et al., Hum Reprod 2013 : However, CXCL6 inhibited trophoblast cell migration and invasion by suppressing MMP-2 activity in human first-trimester interface