Gene interactions and pathways from curated databases and text-mining

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FGF2 — MMP25

Text-mined interactions from Literome

Shimazu et al., J Periodontal Res 2003 : Furthermore, MMP-3 expression induced by bFGF was abrogated by U0126, a specific inhibitor of MEK1/2 and ERK1/2 in mitogen activated protein ( MAP ) kinase pathway, not by PD98059, a specific inhibitor of MEK1
Giunciuglio et al., Int J Oncol 1995 : Also bFGF alone, a heparin dependent factor, alone can induce endothelial and smooth muscle cell invasion, MMP-2 production and PA activity
Sasaki et al., J Biochem 1998 : An MMP inhibitor partially suppressed the release of bFGF , indicating that matrix degradation is at least partially involved in the IL-1 stimulated bFGF release even if increased production of bFGF is related to the release
Andersen et al., Anticancer Res 1998 (Bone Neoplasms...) : The CAPL protein expressed in cell-cultures appear to block the MMP induction by bFGF and Il-1 alpha