◀ Back to HIF1A

HIF1A — MT3

Text-mined interactions from Literome

Kim et al., Biochem Biophys Res Commun 2008 : Metallothionein-III induces HIF-1alpha mediated VEGF expression in brain endothelial cells ... MT-III also increased the accumulation of HIF-1alpha in nuclei and increased HIF-1alpha binding to the VEGF promoter ... However, pretreatment with PD98059 and LY294002 ( ERK1/2 and Akt inhibitors ) inhibited MT-III induced stimulation of HIF-1alpha protein expression and VEGF production
Kojima et al., Kidney Int 2009 : Hypoxia and exogenous metallothionein increased HIF-1alpha protein without changes in its mRNA levels, suggesting protein stabilization