Gene interactions and pathways from curated databases and text-mining

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FOXO1 — MYC

Text-mined interactions from Literome

Bouchard et al., EMBO J 2004 (Cell Transformation, Neoplastic) : Myc induced proliferation and transformation require Akt mediated phosphorylation of FoxO proteins
Gomis et al., Cancer Cell 2006 (Breast Neoplasms...) : We found the transcription factor C/EBPbeta to be essential for TGFbeta induction of the cell cycle inhibitor p15INK4b by a FoxO-Smad complex and repression of c-MYC by an E2F4/5-Smad complex in human epithelial cells
Bouchard et al., Genes Dev 2007 (Lymphoma) : Moreover, constitutive Myc signaling induces a marked increase in nuclear FoxO levels and stimulates binding of FoxO proteins to the Arf locus