Gene interactions and pathways from curated databases and text-mining

◀ Back to FOXO1

FOXO1 — MYLIP

Text-mined interactions from Literome

Guttilla et al., J Biol Chem 2009 (Breast Neoplasms) : Coordinate regulation of FOXO1 by miR-27a , miR-96, and miR-182 in breast cancer cells
Myatt et al., Cancer Res 2010 (Endometrial Neoplasms) : Expression of miR-9 , miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 ... Moreover, induction of FOXO1 in Ishikawa cells by miR inhibitors was accompanied by G1 cell cycle arrest and cell death, and was attenuated by the small interfering RNA mediated downregulation of FOXO1 expression
Small et al., Proc Natl Acad Sci U S A 2010 : Accordingly, PTEN and Foxo1a protein levels are reduced by miR-486 overexpression, which, in turn, enhances PI3K/Akt signaling ... Conversely, inhibition of miR-486 expression enhances the expression of PTEN and Foxo1a and dampens signaling through the PI3K/Akt signaling pathway