Xu et al., Cell stem cell 2008
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NANOG promoter activity is enhanced by TGFbeta/Activin and FGF signaling and is decreased by BMP signaling
Goossens et al., Stem Cells Dev 2013
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By interfering with the FGF signaling pathway, we found functional evidence that miR-218, mainly expressed in the inner cell mass, regulates the NANOG expression in the bovine blastocyst in response to FGF signaling