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NFKBIE — RELA
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
NFKBIE
—
RELA
(direct interaction, two hybrid)
Li et al., Mol Cell Biol 1997
-
IRef Biogrid Interaction:
NFKBIE
—
RELA
(direct interaction, pull down)
Li et al., Mol Cell Biol 1997
-
IRef Biogrid Interaction:
NFKBIE
—
RELA
(direct interaction, two hybrid)
Wang et al., Molecular systems biology 2011
-
IRef Biogrid Interaction:
NFKBIE
—
RELA
(physical association, affinity chromatography technology)
Li et al., Mol Cell Biol 1997
-
MIPS CORUM TNF-alpha/NF-kappa B signaling complex (CHUK, KPNA3, NFKB2, NFKBIB, REL, IKBKG, NFKB1, NFKBIE, RELB, NFKBIA, RELA, TNIP2):
TNF-alpha/NF-kappa B signaling complex (CHUK, KPNA3, NFKB2, NFKBIB, REL, IKBKG, NFKB1, NFKBIE, RELB, NFKBIA, RELA, TNIP2) complex (CHUK-IKBKG-KPNA3-NFKB1-NFKB2-NFKBIA-NFKBIB-NFKBIE-REL-RELA-RELB-TNIP2)
Bouwmeester et al., Nat Cell Biol 2004
-
MIPS CORUM CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 complex:
CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 complex complex (CHUK-COPB2-IKBKG-NFKB1-NFKB2-NFKBIA-NFKBIE-REL-RELA-SPAG9-TNIP1-TNIP2)
Bouwmeester et al., Nat Cell Biol 2004
-
MIPS CORUM IKB(epsilon)-RELA-cREL complex:
IKB(epsilon)-RELA-cREL complex complex (NFKBIE-REL-RELA)
Whiteside et al., EMBO J 1997
-
IRef Corum Interaction:
Complex of REL-NFKBIE-RELA
(association, anti bait coimmunoprecipitation)
Whiteside et al., EMBO J 1997
-
IRef Corum Interaction:
Complex of 13 proteins
(association, tandem affinity purification)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Corum Interaction:
Complex of 13 proteins
(association, tandem affinity purification)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Dip Interaction:
NFKBIE
—
RELA
(physical association, tandem affinity purification)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Hprd Interaction:
Complex of 145 proteins
(in vivo)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Hprd Interaction:
Complex of 145 proteins
(in vivo)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Hprd Interaction:
NFKBIE
—
RELA
(in vitro)
Bouwmeester et al., Nat Cell Biol 2004, Li et al., Mol Cell Biol 1997
-
IRef Hprd Interaction:
NFKBIE
—
RELA
(in vivo)
Bouwmeester et al., Nat Cell Biol 2004, Li et al., Mol Cell Biol 1997
-
IRef Intact Interaction:
NFKBIE
—
RELA
(physical association, tandem affinity purification)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Intact Interaction:
NFKBIE
—
RELA
(physical association, two hybrid)
Wang et al., Molecular systems biology 2011
-
IRef Intact Interaction:
NFKBIE
—
RELA
(physical association, two hybrid array)
Wang et al., Molecular systems biology 2011
-
IRef Ophid Interaction:
NFKBIE
—
RELA
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
-
IRef Ophid Interaction:
NFKBIE
—
RELA
(aggregation, confirmational text mining)
Bouwmeester et al., Nat Cell Biol 2004
Text-mined interactions from Literome
Doerre et al., J Immunol 2005
:
We propose an important
role for
IkappaBepsilon in the differential regulation of nuclear
NF-kappaB activity in stimulated B cells
Kearns et al., J Cell Biol 2006
(Inflammation) :
Upon stimulation,
NF-kappaB induced transcription of
IkappaBepsilon is delayed, relative to that of IkappaBalpha, rendering the two negative feedback loops to be in antiphase
Whiteside et al., EMBO J 1997
:
I kappa B epsilon , a novel member of the I kappa B family,
controls RelA and cRel
NF-kappa B activity ...
I kappa B epsilon , a novel member of the I kappa B family,
controls RelA and cRel NF-kappa B activity
O'Connell et al., J Biol Chem 1998
:
Phosphorylation of the IkappaB cytoplasmic inhibitors, IkappaBalpha, IkappaBbeta, and
IkappaBepsilon , by these kinases
triggers proteolytic degradation and the release of
NF-kappaB/Rel proteins into the nucleus