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FOXO1 — NOS2
Text-mined interactions from Literome
Puthanveetil et al., Free Radic Biol Med 2011
:
PA-treated cardiomyocytes showed a substantial increase in TG accumulation, accompanied by amplification of nuclear migration of phospho-p38 and
FoxO1 ,
iNOS induction , and translocation of CD36 to the plasma membrane
Puthanveetil et al., J Mol Cell Cardiol 2012
(Diabetes Mellitus, Experimental...) :
Our data suggests a role for
FoxO1 mediated
iNOS induced S-nitrosylation of target proteins like GAPDH and caspase-3 in initiating cardiac cell death following hyperglycemia, and could explain the impact of glycemic control in preventing cardiovascular disease in patients with diabetes