Gene interactions and pathways from curated databases and text-mining

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NR4A1 — PTH

Text-mined interactions from Literome

Tetradis et al., Biochem Biophys Res Commun 2001 : Regulation of the nuclear orphan receptor Nur77 in bone by parathyroid hormone ... We show that PTH induced the expression of Nur77 , a member of the NGFI-B subfamily of nuclear orphan receptors in bone
Pirih et al., Biochem Biophys Res Commun 2005 : In calvaria and long bone, PTH induced expression of each NR4A gene was detectable at 10 microg/kg i.p. with maximum induction at 40-80 microg/kg ... PTH ( 3-34 ) did not induce NR4A mRNA levels in calvaria, long bone, and kidney in vivo, confirming our in vitro results that NR4A genes are induced primarily through the cAMP-PKA pathway ... The magnitude of PTH induced NR4A expression was comparable in vivo and in vitro