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AKT3 — NTRK3
Text-mined interactions from Literome
Tognon et al., Cancer Res 2001
(Cell Transformation, Neoplastic...) :
The chimeric protein tyrosine kinase
ETV6-NTRK3 requires both Ras-Erk1/2 and
PI3-kinase-Akt signaling for fibroblast transformation ... We now report that
ETV6-NTRK3 expression in NIH3T3 cells
leads to constitutive activation of Mek1 and
Akt , as well as to constitutively high expression of cyclin D1
Jin et al., Cancer Res 2007
(Cell Transformation, Neoplastic) :
Here, we define some aspects of the molecular mechanisms regulating
ETV6-NTRK dependent Ras-Erk1/2 and
PI3K-Akt activation
Jin et al., J Biol Chem 2008
(Cell Transformation, Neoplastic) :
Here we define some aspects of the molecular mechanisms regulating
TrkC dependent Ras-Erk1/2 and
PI3K/Akt activation
Ivanov et al., Oncogene 2013
(Carcinoma, Adenoid Cystic...) :
NT-3 stimulation of U2OS cells with ectopic
TrkC expression triggered TrkC phosphorylation and
resulted in Ras, Erk 1/2 and
Akt activation, as well as VEGFR1 phosphorylation