Gene interactions and pathways from curated databases and text-mining

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AKT3 — NTRK3

Text-mined interactions from Literome

Tognon et al., Cancer Res 2001 (Cell Transformation, Neoplastic...) : The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation ... We now report that ETV6-NTRK3 expression in NIH3T3 cells leads to constitutive activation of Mek1 and Akt , as well as to constitutively high expression of cyclin D1
Jin et al., Cancer Res 2007 (Cell Transformation, Neoplastic) : Here, we define some aspects of the molecular mechanisms regulating ETV6-NTRK dependent Ras-Erk1/2 and PI3K-Akt activation
Jin et al., J Biol Chem 2008 (Cell Transformation, Neoplastic) : Here we define some aspects of the molecular mechanisms regulating TrkC dependent Ras-Erk1/2 and PI3K/Akt activation
Ivanov et al., Oncogene 2013 (Carcinoma, Adenoid Cystic...) : NT-3 stimulation of U2OS cells with ectopic TrkC expression triggered TrkC phosphorylation and resulted in Ras, Erk 1/2 and Akt activation, as well as VEGFR1 phosphorylation