Gene interactions and pathways from curated databases and text-mining

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CASP6 — NUP214

Text-mined interactions from Literome

Ferrando-May et al., Cell Death Differ 2001 : Redistribution of import factors and mRNA, as well as nuclear permeabilisation, occur prior to caspase mediated nucleoporin cleavage
Corsten et al., Cancer Res 2007 (Brain Neoplasms...) : With the use of locked nucleic acid ( LNA ) -antimiR-21 oligonucleotides, bimodal imaging vectors, and neural precursor cells (NPC) expressing a secretable variant of the cytotoxic agent tumor necrosis factor related apoptosis inducing ligand ( S-TRAIL ), we show that the combined suppression of miR-21 and NPC-S-TRAIL leads to a synergistic increase in caspase activity and significantly decreased cell viability in human glioma cells in vitro