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Härle et al., Virology 2001
:
Viral lytic gene transcript and viral protein levels were lower in IFN-beta- versus IFN-alpha 2-transfected cells, which coincided with elevated PKR and OAS transcript levels and increased total STAT1 and phosphorylated STAT1 ( Y701 ) protein levels in the IFN-beta transfected cells
Pulit-Penaloza et al., Virology 2012
:
Activation of Oas1a gene expression by type I IFN requires both STAT1 and STAT2 while only STAT2 is required for Oas1b activation
Colonne et al., J Med Microbiol 2013
:
Increased STAT1 phosphorylation in HMECs subjected to UBP43 knockdown led to transcriptional activation of OAS1 , MX1 and GBP1, confirming the negative regulatory role of UBP43
Will et al., J Immunol 1996
(Rhabdoviridae Infections) :
The virus resistance induced was accompanied by enhanced expression of 2'-5 ' oligoadenylate synthetase and constitutive activation of STAT1 ( signal transducers and activators of transcription )