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ABL1 — PCBP2

Text-mined interactions from Literome

Perrotti et al., Nat Genet 2002 (Blast Crisis...) : Our results indicate that BCR-ABL regulates the expression of C/EBPalpha by inducing hnRNP E2-which inhibits the translation of CEBPA mRNA
Chen et al., Chin J Cancer 2006 : The abnormal expression of poly ( rC ) -binding protein E2 ( hnRNP E2 ) induced by BCR/ABL plays an important role in blast crisis of chronic myeloid leukemia ( CML )
Perrotti et al., Clin Cancer Res 2007 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive...) : Here, we summarize the effects of increased BCR/ABL oncogenic activity on the expression and function of RNA binding proteins ( e.g., FUS, hnRNP A1, hnRNP E2 , hnRNP K, and La/SSB ) with posttranscriptional and translational regulatory activities and their importance for the phenotype of BCR/ABL transformed hematopoietic progenitors
Chang et al., Blood 2007 (Blast Crisis...) : In fact, high levels of p210-BCR/ABL are required for enhanced hnRNP-E2 expression, which depends on phosphorylation of hnRNP-E2 serines 173, 189, and 272 and threonine 213 by the BCR/ABL activated MAPK(ERK1/2)