Gene interactions and pathways from curated databases and text-mining

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FOXO1 — PDHX

Text-mined interactions from Literome

Mallinson et al., J Physiol 2012 (Body Weight...) : We previously reported that statin myopathy is associated with impaired carbohydrate ( CHO ) oxidation in fast-twitch rodent skeletal muscle, which we hypothesised occurred as a result of forkhead box protein O1 (FOXO1) mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) gene transcription
Piao et al., J Mol Med (Berl) 2013 (Hypertension, Pulmonary...) : FOXO1 mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension : therapeutic benefits of dichloroacetate