Gene interactions and pathways from curated databases and text-mining

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FOXO1 — PDK1

Text-mined interactions from Literome

Rena et al., EMBO J 2002 : IGF-1 stimulates the phosphorylation of Thr24, Ser256, Ser319, Ser322 and Ser325 in embryonic stem ( ES ) cells, but not in PDK1-/- ES cells, providing genetic evidence that PDK1 ( the upstream activator of PKB ) is required for the phosphorylation of FKHR in mammalian cells
Kawano et al., Diabetes 2012 (Insulin Resistance...) : Thus, Pdk1 regulated macrophage infiltration by inhibiting Foxo1 induced Ccr2 expression