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FOXO1 — PGC
Text-mined interactions from Literome
Daitoku et al., Diabetes 2003
:
Coexpression of
FKHR stimulates the
PGC-1 promoter activity via interaction with the IRSs, while coexpression of FKHR ( 3A ), in which the three putative PKB sites in FKHR are mutated, mainly abolishes the suppressive effect of PKB
Geng et al., Am J Pathol 2011
(Cachexia) :
PGC-1a promotes nitric oxide antioxidant defenses and
inhibits FOXO signaling against cardiac cachexia in mice
Felder et al., J Biol Chem 2011
:
Here we describe a novel human liver-specific
PGC-1a transcript that results from alternative promoter usage and is
induced by
FOXO1 as well as glucocorticoids and cAMP-response element binding protein signaling but is not present in other mammals