Gene interactions and pathways from curated databases and text-mining

◀ Back to FOS

FOS — PGF

Pathways - manually collected, often from reviews:

  • KEGG Pathways in cancer: FOS → FIGF/PGF/VEGFA/VEGFB/VEGFC (gene expression, expression)

Text-mined interactions from Literome

Holmes et al., FEBS Lett 2004 : In contrast, PlGF induced c-Fos expression less strongly than VEGF, and whereas VEGF strongly upregulated tissue factor mRNA, PlGF had a negligible effect ... PlGF induced c-Fos expression in porcine aortic endothelial cells specifically expressing Flt-1, and FosB expression in the monocytic RAW 264.7 cell line expressing endogenous Flt-1 ... These findings show for the first time that VEGF and PlGF induce mRNA expression of the transcription factors FosB and c-Fos , and suggest that these factors may play a role in the biological responses mediated by PlGF and Flt-1
Diaz et al., Domest Anim Endocrinol 2013 : At 10 h after PGF2a there was elevated FOSB mRNA in day-17 ( 771 % ) but not day-9 CL and no PGF2a induced change in FOS , JUN, JUND, and JUNB mRNA in day-9 or day-17 CL. Treatment with PGF2a increased mRNA for AP-1-responsive genes, CCL2 at 0.5 h ( 202 % ) and CCL2 and SERPINE1 at 10 h ( 719 % and 1,515 % ), only in day-17 CL