Gene interactions and pathways from curated databases and text-mining

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CXCL2 — PI3

Text-mined interactions from Literome

Gálvez et al., J Biol Chem 2005 : Investigation of the signaling pathways involved in chemokine induced MT1-MMP activity in ECs revealed that CCL2 and CXCL8 induced cortical actin polymerization and sustained activation of phosphatidylinositol 3-kinase (PI3K) and the small GTPase Rac
Lin et al., J Biol Chem 2011 : In this study, we further investigated the roles of Rac1, phosphoinositide 3-kinase (PI3K) , and Akt in thrombin induced NF-?B activation and IL-8/CXCL8 expression