Gene interactions and pathways from curated databases and text-mining

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PI3 — PRKAG2

Text-mined interactions from Literome

Zong et al., PloS one 2012 (MAP Kinase Signaling System) : Meanwhile, PI3-K is essential for resveratrol mediated phosphorylation of AMPK and expression of SIRT1
Suzuki et al., Mol Cell 2013 : Surprisingly, PI3K-Akt signaling, which is a major anabolic signaling and normally inhibits GSK3 activity, promotes GSK3 phosphorylation and inhibition of AMPK , thus revealing how AMPK senses anabolic environments in addition to cellular energy levels