◀ Back to INS
INS — PLA2G4A
Text-mined interactions from Literome
Jones et al., Diabetes 2004
:
Our results suggest that
cPLA(2) is not
required for the initiation of
insulin secretion from beta-cells, but that it plays an important role in the maintenance of beta-cell insulin stores
Isenovic et al., Cell Biol Int 2009
:
Therefore, this investigation used primary cultured rat VSMCs to examine the role of PI3K and ERK1/2 in the INS dependent phosphorylation of
cPLA2 and proliferation
induced by
INS ... Similarly, the PI3K inhibitor LY294002 ( 10 microM ; 15 min ) and ERK1/2 inhibitor PD98059 ( 20 microM ; 15 min ) abolished the
INS mediated increase in
cPLA2 phosphorylation by 59 % ( p < 0.001 ), and by 75 % ( p < 0.001 ), respectively