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INS — PLA2G4A

Text-mined interactions from Literome

Jones et al., Diabetes 2004 : Our results suggest that cPLA(2) is not required for the initiation of insulin secretion from beta-cells, but that it plays an important role in the maintenance of beta-cell insulin stores
Isenovic et al., Cell Biol Int 2009 : Therefore, this investigation used primary cultured rat VSMCs to examine the role of PI3K and ERK1/2 in the INS dependent phosphorylation of cPLA2 and proliferation induced by INS ... Similarly, the PI3K inhibitor LY294002 ( 10 microM ; 15 min ) and ERK1/2 inhibitor PD98059 ( 20 microM ; 15 min ) abolished the INS mediated increase in cPLA2 phosphorylation by 59 % ( p < 0.001 ), and by 75 % ( p < 0.001 ), respectively