Gene interactions and pathways from curated databases and text-mining

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EGF — PLAT

Text-mined interactions from Literome

Park et al., Biol Reprod 1999 : In the presence of EGF , however, some activity of tPA-PAI was detected at 12 h of culture
George et al., Blood Coagul Fibrinolysis 1990 : We found that, under conditions in which EGF had no effect on tPA activity, tPA antigen increased with a concomitant rise of tPA/PAI-1 complexes, indicating the action of an inhibitor
Ayub et al., J Mol Endocrinol 1990 : The aim of the present study was to determine whether specific tPA receptors or EGF receptors mediate the binding of tPA to cells and whether tPA possesses intrinsic mitogenic activity
Galway et al., Endocrinology 1989 : While FSH and GnRH are known to stimulate accumulation of tissue-type plasminogen activator (tPA) mRNA in granulosa cells, studies using nonovarian cells have shown stimulation of tPA by EGF
Sato et al., Exp Cell Res 1993 (Neovascularization, Pathologic) : EGF and TGF-alpha induced expression of tPA in HOME cells, while IGF-1 and HGF did not
Ueda et al., Hum Cell 1993 (Adenocarcinoma...) : Effects of EGF on cell growth, DNA synthesis, and laminin, collagen IV, and tissue plasminogen activator (t-PA) production of human uterine cervical adenocarcinoma cell line OMC-4 were examined, together with the characteristics of its EGF receptors