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PLAU — TIMP1
Text-mined interactions from Literome
Shibata et al., J Periodontol 1999
:
TIMP-1 controls the synthesis of
uPA in the PDL cells
Festuccia et al., Anticancer Res 2000
(Prostatic Neoplasms) :
High levels of
TIMP1 and PAI1 present in S variant
reduce MMP9 and
uPA activities, respectively
Gillette et al., Tumori 2003
:
We
detected MMP-7,
urokinase plasminogen activator (uPA) and PAI-1 in both Matrigels, TIMP-2 was detected only in regular Matrigel and no MMP-1 or
TIMP-1 was detected in either matrix
Eddy et al., Kidney Int 1998
(Fibrosis...) :
Compared with the untreated hypercholesterolemic group, antioxidant therapy
induced significant reductions in renal mRNA levels for procollagen III ( to 60 % of untreated levels ), collagen IV ( 60 % ), and
TIMP-1 ( 20 % ), while
uPA levels were significantly increased ( to 210 % )