Gene interactions and pathways from curated databases and text-mining

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ADCYAP1 — PLD3

Text-mined interactions from Literome

Dejda et al., Ann N Y Acad Sci 2006 : Their effects on PLC-IP3/DAG were weaker, while only PACAP and VIP ( 0.1-5 microM ) significantly stimulated PLD activity
Morisset et al., Cell Signal 1995 (Pancreatic Neoplasms) : PACAP-38 and -27 caused a dose dependent and parallel activation of tyrosine kinase and PLD an effect prevented by the antagonist PACAP 7-38 ... Finally, PACAP stimulated tyrosine kinase and PLD activities are both inhibited by cell 's preincubation with genistein and pertussis toxin ... PACAP can induce concomitant activation of tyrosine kinase and PLD ; this finding and the observation that inhibition of these two enzymes inhibited PACAP induced AR4-2J cell growth strongly suggests that they are intimately involved in the overall process of PACAP induced AR4-2J cell proliferation