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Lee et al., Horm Metab Res 2011
:
In the present study, the relationships between NIS, CHOP, and
p38 MAPK, and the
effects of ATRA on NIS and
CHOP expression as well as on p38 MAPK activation under condition of ER stress in thyroid cells were investigated
Park et al., Biochem Pharmacol 2011
:
Pretreatment with the pan-caspase inhibitor z-VAD-fmk prevented MG132 induced apoptotic caspase cascade, but allowed upregulation of Grp78/BiP and
CHOP/GADD153 levels,
activation of JNK and
p38MAPK , d?m loss, and cleavage of procaspase-9 ( 47kDa ) to active form ( 35kDa )