Kuijk et al., Reproduction 2009
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FGF decreased expression of PLZF and enhanced the expression of pluripotency related gene POU5F1 and Sertoli cell marker GATA4
Ding et al., J Cell Physiol 2010
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Furthermore, downregulation of Oct3/4 in hESC occurs following treatment with an FGFR inhibitor, suggesting that FGF signaling may regulate Oct3/4 expression