Gene interactions and pathways from curated databases and text-mining

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FOXO1 — PPP2R1A

Text-mined interactions from Literome

Ni et al., Proc Natl Acad Sci U S A 2007 (Insulin Resistance) : In addition, FoxO activity suppresses protein phosphatase 2A (PP2A) and disrupts Akt-PP2A and Akt-calcineurin interactions
Yan et al., J Biol Chem 2008 : PP2A regulates the pro-apoptotic activity of FOXO1
Bertoli et al., Oncogene 2009 (Starvation) : PP2A associates more tightly with Akt in CAPNS1 knockout cells, indicating that PP2A is involved in calpain mediated FoxO regulation
Galbo et al., PloS one 2011 (Insulin Resistance) : Furthermore, inhibition of PP2A by specific inhibitors increased insulin stimulated activation of Akt and phosphorylation of FoxO1 and Gsk3a