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JUN — PPP2R1A
Text-mined interactions from Literome
Al-Murrani et al., Biochem J 1999
:
Expression of
I2PP2A , an inhibitor of protein phosphatase 2A,
induces c-Jun and
AP-1 activity ... Expression of
I2PP2A , an inhibitor of protein phosphatase 2A,
induces c-Jun and AP-1 activity
RamÃrez et al., J Cell Biochem 2005
(Carcinoma...) :
Since the inhibition of
AP-1 activity following atRA treatment of CA-OV3 cells was abolished in the
presence of specific
PP2A inhibitors, it is likely that PP2A plays an important role in the atRA induced repression of AP-1
Tsuchiya et al., Oncogene 2007
:
Moreover, the inhibitors of
PP2A restored the levels of
c-Jun phosphorylated at Ser-63
Alberts et al., Mol Cell Biol 1993
:
PP2A , but not PP1,
potentiated serum induced
c-Jun expression, which has been previously shown to be autoregulated by AP-1 itself ... Consistent with these results, PP2A dephosphorylated c-Jun on negative regulatory sites in vitro, suggesting one possible direct mechanism for the
effects of
PP2A on
AP-1 activity