Gene interactions and pathways from curated databases and text-mining

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GSK3B — PRKAB2

Text-mined interactions from Literome

Horike et al., J Biol Chem 2008 : Although a previous study found TORC2 phosphorylation to be involved in the suppression of AMPK mediated CRE transcriptional activity, we herein present evidence that glycogen synthase kinase 3beta ( GSK3beta ) phosphorylation induced by AMPK also plays an important role ... Furthermore, AMPK mediated GSK3beta phosphorylation was inhibited by an Akt-specific inhibitor in HepG2 cells, suggesting involvement of the Akt pathway
Choi et al., Biochem Pharmacol 2010 : AMPK mediated GSK3beta inhibition by isoliquiritigenin contributes to protecting mitochondria against iron catalyzed oxidative stress ... Moreover, the AMPK activation led to GSK3beta phosphorylation
Ha et al., J Ethnopharmacol 2010 : Compounds 1, 4, 5-12, and 14 displayed considerable effects on hepatic glucose production, AMPK activation , and phosphorylation of GSK-3beta in HepG2 cells under high glucose conditions