Gene interactions and pathways from curated databases and text-mining

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GATA4 — PRKACB

Text-mined interactions from Literome

Tremblay et al., Endocrinology 2002 : We now report that GATA-4 is phosphorylated in MA-10 cells in response to cAMP and in heterologous CV-1 cells, GATA-4 transcriptional activity is stimulated by PKA ... We now report that GATA-4 is phosphorylated in MA-10 cells in response to cAMP and in heterologous CV-1 cells, GATA-4 transcriptional activity is stimulated by PKA
Tremblay et al., J Biol Chem 2003 : We now show that the rapid phosphorylation of GATA-4 induced by cAMP in vivo can be blocked by a PKA-specific inhibitor but not by mitogen activated protein kinase inhibitors, indicating that GATA-4 is predominantly phosphorylated by PKA in response to cAMP in gonadal cells ... Finally, PKA dependent phosphorylation of GATA-4 also led to enhanced recruitment of the CREB binding protein coactivator
Tremblay et al., J Steroid Biochem Mol Biol 2003 : GATA-4 phosphorylation is mediated by PKA