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CASP8 — PRKCG

Text-mined interactions from Literome

Lin et al., Curr Eye Res 2007 (Diabetes Mellitus, Experimental) : PKC-gamma activation was measured by enzyme activity assay and by Western blotting to show autophosphorylation on Thr514. Cellular insulin-like growth factor-1 (IGF-1), PKC-gamma phosphorylation of Cx43 on Ser368, and activation of phospholipase C-gamma 1 ( PLC-gamma 1 ), extracellular signal regulated kinase ( ERK1/2 ), and caspase-3 were determined by Western blotting
Lin et al., Biochem Biophys Res Commun 2007 (Spinocerebellar Ataxias) : Pre-incubation with C1B1 peptides completely abolished these SCA14 effects on ER stress and caspase-3 activation, suggesting that C1B1 peptides protect cells from apoptosis through inhibition of gap junctions by restoration of PKCgamma control of gap junctions, which may result in neuroprotection in SCA14
Aires et al., Mol Pharmacol 2007 (Calcium Signaling) : Chemical inhibition of PKCgamma/delta and of SOC/CRAC channels significantly attenuated both DHA stimulated ROS production and caspase-3 activity