Gene interactions and pathways from curated databases and text-mining

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PRR7 — TNF

Text-mined interactions from Literome

Zhong et al., J Biol Chem 2007 (MAP Kinase Signaling System) : The JNK and p38 MAPK groups are major PRR effectors and are key to the PRR dependent induction and release of proinflammatory cytokines such as tumor necrosis factor and interleukin-8
Zubcevic et al., Hypertension 2013 (Hypertension) : Finally, PRR activation in SHR neuronal cultures by prorenin activated nuclear factor-?B and increased mRNA levels of interleukin-1ß ( 250-fold ), tumor necrosis factor-a ( 32-fold ), interleukin-6 ( 35-fold ), C-C motif ligand 5 ( 12-fold ), and interleukin-10 ( 7-fold ) in a nuclear factor-?B dependent but angiotensin II type 1 receptor independent manner