Gene interactions and pathways from curated databases and text-mining

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KLK3 — PTPN1

Text-mined interactions from Literome

Wu et al., Acta Pharmacol Sin 2005 (Diabetes Mellitus, Experimental...) : To examine the effects of Astragalus polysaccharide (APS) , a component of an aqueous extract of Astragalus membranaceus roots, on protein tyrosine phosphatase 1B (PTP1B) , a negative regulator of insulin-receptor (IR) signal transduction, and its potential role in the amelioration of insulin resistance ... APS reduced both PTP1B protein level and activity in the muscle, but not in the liver of TIIDM rats
Zhao et al., Molecules (Basel, Switzerland) 2012 (Insulin Resistance) : Moreover, the increases in protein-tyrosine phosphatase-1B (PTP1B) protein level and NF-?B activation associated with palmitate treatment were also prevented by APS