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KLK3 — PTPN1
Text-mined interactions from Literome
Wu et al., Acta Pharmacol Sin 2005
(Diabetes Mellitus, Experimental...) :
To examine the
effects of
Astragalus polysaccharide (APS) , a component of an aqueous extract of Astragalus membranaceus roots, on
protein tyrosine phosphatase 1B (PTP1B) , a negative regulator of insulin-receptor (IR) signal transduction, and its potential role in the amelioration of insulin resistance ...
APS reduced both
PTP1B protein level and activity in the muscle, but not in the liver of TIIDM rats
Zhao et al., Molecules (Basel, Switzerland) 2012
(Insulin Resistance) :
Moreover, the increases in
protein-tyrosine phosphatase-1B (PTP1B) protein level and NF-?B activation associated with palmitate treatment were also
prevented by
APS