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CAPN11 — PTPN5

Text-mined interactions from Literome

Xu et al., J Neurosci 2009 : Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain mediated cleavage of STEP
Mesfin et al., J Neurotrauma 2012 (Brain Injuries...) : STEP ( 61 ) expression progressively increases after sublethal stretch with no change in calpain mediated STEP ( 33 ) formation, while lethal stretch injury results in STEP ( 33 ) formation via a NR2B containing NMDA receptor pathway within 1 h of injury ... In summary, these data demonstrate that previously characterized pathways of STEP regulation via the NMDA receptor are generally conserved in mechanical injury, and suggest that calpain mediated cleavage of STEP ( 33 ) should be further examined as an early marker of neuronal fate after stretch injury