◀ Back to RAD17

RAD17 — RAD9A

Pathways - manually collected, often from reviews:

• BioCarta role of brca1 brca2 and atr in cancer susceptibility: ATR/ATRIP/ATM complex (ATR-TREX1-ATM) → Hus1/Rad1/Rad9/Rad17 complex (HUS1-RAD1-RAD9A-RAD17) (modification, activates)
  
• NCI Pathway Database ATR signaling pathway: RAD9/RAD1/HUS1 complex (RAD9A-RAD1-HUS1) → RPA/RAD17/RFC2-5/9-1-1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1) (modification, collaborate)
  Zou et al., Genes Dev 2002, Bermudez et al., Proc Natl Acad Sci U S A 2003, Zou et al., Proc Natl Acad Sci U S A 2003, Ellison et al., PLoS Biol 2003, Xu et al., Mol Cell Biol 2008, Medhurst et al., J Cell Sci 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RAD9/RAD1/HUS1 complex (RAD9A-RAD1-HUS1) → RPA/RAD17/RFC2-5 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2) (modification, collaborate)
  Zou et al., Genes Dev 2002, Bermudez et al., Proc Natl Acad Sci U S A 2003, Zou et al., Proc Natl Acad Sci U S A 2003, Ellison et al., PLoS Biol 2003, Xu et al., Mol Cell Biol 2008, Medhurst et al., J Cell Sci 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/RAD17/RFC2-5/9-1-1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1) → RPA/RAD17/RFC2-5 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2) (modification, collaborate)
  Zou et al., Genes Dev 2002, Bermudez et al., Proc Natl Acad Sci U S A 2003, Zou et al., Proc Natl Acad Sci U S A 2003, Ellison et al., PLoS Biol 2003, Xu et al., Mol Cell Biol 2008, Medhurst et al., J Cell Sci 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-TIMELESS-TIPIN) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN/CHK1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-CHEK1-TIMELESS-TIPIN) (modification, collaborate)
  Liu et al., Genes Dev 2000, Zhao et al., Mol Cell Biol 2001, Zou et al., Genes Dev 2002, Zou et al., Science 2003, Liu et al., Mol Cell Biol 2006, Wang et al., Mol Cell 2006, Unsal-Kaçmaz et al., Mol Cell Biol 2007, Delacroix et al., Genes Dev 2007, Choi et al., Proc Natl Acad Sci U S A 2007, Lindsey-Boltz et al., J Biol Chem 2009, Kemp et al., J Biol Chem 2010, Choi et al., Proc Natl Acad Sci U S A 2010
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-TIMELESS-TIPIN) → CHK1 (CHEK1) (modification, collaborate) Liu et al., Genes Dev 2000, Zhao et al., Mol Cell Biol 2001, Zou et al., Genes Dev 2002, Zou et al., Science 2003, Liu et al., Mol Cell Biol 2006, Wang et al., Mol Cell 2006, Unsal-Kaçmaz et al., Mol Cell Biol 2007, Delacroix et al., Genes Dev 2007, Choi et al., Proc Natl Acad Sci U S A 2007, Lindsey-Boltz et al., J Biol Chem 2009, Kemp et al., J Biol Chem 2010, Choi et al., Proc Natl Acad Sci U S A 2010
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN/CHK1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-CHEK1-TIMELESS-TIPIN) → CHK1 (CHEK1) (modification, collaborate) Liu et al., Genes Dev 2000, Zhao et al., Mol Cell Biol 2001, Zou et al., Genes Dev 2002, Zou et al., Science 2003, Liu et al., Mol Cell Biol 2006, Wang et al., Mol Cell 2006, Unsal-Kaçmaz et al., Mol Cell Biol 2007, Delacroix et al., Genes Dev 2007, Choi et al., Proc Natl Acad Sci U S A 2007, Lindsey-Boltz et al., J Biol Chem 2009, Kemp et al., J Biol Chem 2010, Choi et al., Proc Natl Acad Sci U S A 2010
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: YWHAZ (YWHAZ) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-TIMELESS-TIPIN) (modification, activates)
  Jiang et al., J Biol Chem 2003, Smits et al., Curr Biol 2006
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: YWHAZ (YWHAZ) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN/CHK1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-CHEK1-TIMELESS-TIPIN) (modification, activates)
  Jiang et al., J Biol Chem 2003, Smits et al., Curr Biol 2006
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-TIMELESS-TIPIN) → CHK1 (CHEK1) (modification, collaborate) Jiang et al., J Biol Chem 2003, Smits et al., Curr Biol 2006
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-TIMELESS-TIPIN) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN/CHK1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-CHEK1-TIMELESS-TIPIN) (modification, collaborate)
  Jiang et al., J Biol Chem 2003, Smits et al., Curr Biol 2006
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: CHK1 (CHEK1) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN/CHK1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-CHEK1-TIMELESS-TIPIN) (modification, collaborate)
  Jiang et al., J Biol Chem 2003, Smits et al., Curr Biol 2006
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP) → RPA/ATR/ATRIP complex (RPA1-RPA2-ATR-ATRIP) (modification, collaborate)
  Bao et al., Nature 2001, Zou et al., Genes Dev 2002, Medhurst et al., J Cell Sci 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP) → RPA/RAD17/RFC2-5/9-1-1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1) (modification, collaborate)
  Bao et al., Nature 2001, Zou et al., Genes Dev 2002, Medhurst et al., J Cell Sci 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP complex (RPA1-RPA2-ATR-ATRIP) → RPA/RAD17/RFC2-5/9-1-1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1) (modification, collaborate)
  Bao et al., Nature 2001, Zou et al., Genes Dev 2002, Medhurst et al., J Cell Sci 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CDC6 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CDC6) → CDC6 (CDC6) (modification, collaborate) Yoshida et al., J Cell Sci 2010
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CDC6 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CDC6) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1) (modification, collaborate)
  Yoshida et al., J Cell Sci 2010
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database ATR signaling pathway: CDC6 (CDC6) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1) (modification, collaborate)
  Yoshida et al., J Cell Sci 2010
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164) → TIMELESS/TIPIN complex (TIMELESS-TIPIN) (modification, collaborate)
  Unsal-Kaçmaz et al., Mol Cell Biol 2007, Kemp et al., J Biol Chem 2010
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-TIMELESS-TIPIN) (modification, collaborate)
  Unsal-Kaçmaz et al., Mol Cell Biol 2007, Kemp et al., J Biol Chem 2010
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database ATR signaling pathway: TIMELESS/TIPIN complex (TIMELESS-TIPIN) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-TIMELESS-TIPIN) (modification, collaborate)
  Unsal-Kaçmaz et al., Mol Cell Biol 2007, Kemp et al., J Biol Chem 2010
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database ATR signaling pathway: CLASPIN (CLSPN) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-TIMELESS-TIPIN) (modification, collaborate)
  Wang et al., Mol Cell 2006
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database ATR signaling pathway: CLASPIN (CLSPN) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-TIMELESS-TIPIN) (modification, collaborate)
  Wang et al., Mol Cell 2006
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN/CLASPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-CLSPN-TIMELESS-TIPIN) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164/TIMELESS/TIPIN complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164-TIMELESS-TIPIN) (modification, collaborate)
  Wang et al., Mol Cell 2006
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database ATR signaling pathway: TopBP1 (TOPBP1) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP) (modification, collaborate)
  Bao et al., Nature 2001, Zou et al., Genes Dev 2002, Kumagai et al., Cell 2006, Ball et al., Mol Cell Biol 2007, Delacroix et al., Genes Dev 2007, Choi et al., Proc Natl Acad Sci U S A 2007, Mordes et al., Genes Dev 2008, Medhurst et al., J Cell Sci 2008, Vassin et al., J Cell Sci 2009, Choi et al., Proc Natl Acad Sci U S A 2010
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: TopBP1 (TOPBP1) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1) (modification, collaborate)
  Bao et al., Nature 2001, Zou et al., Genes Dev 2002, Kumagai et al., Cell 2006, Ball et al., Mol Cell Biol 2007, Delacroix et al., Genes Dev 2007, Choi et al., Proc Natl Acad Sci U S A 2007, Mordes et al., Genes Dev 2008, Medhurst et al., J Cell Sci 2008, Vassin et al., J Cell Sci 2009, Choi et al., Proc Natl Acad Sci U S A 2010
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1) (modification, collaborate)
  Bao et al., Nature 2001, Zou et al., Genes Dev 2002, Kumagai et al., Cell 2006, Ball et al., Mol Cell Biol 2007, Delacroix et al., Genes Dev 2007, Choi et al., Proc Natl Acad Sci U S A 2007, Mordes et al., Genes Dev 2008, Medhurst et al., J Cell Sci 2008, Vassin et al., J Cell Sci 2009, Choi et al., Proc Natl Acad Sci U S A 2010
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: SMARCAL1 (SMARCAL1) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1) (modification, collaborate)
  Bansbach et al., Genes Dev 2009
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: SMARCAL1 (SMARCAL1) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/SMARCAL1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-SMARCAL1) (modification, collaborate)
  Bansbach et al., Genes Dev 2009
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/SMARCAL1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-SMARCAL1) (modification, collaborate)
  Bansbach et al., Genes Dev 2009
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164) → CEP164 (CEP164) (modification, collaborate) Sivasubramaniam et al., Genes Dev 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1/CEP164 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1-CEP164) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1) (modification, collaborate)
  Sivasubramaniam et al., Genes Dev 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database ATR signaling pathway: CEP164 (CEP164) → RPA/ATR/ATRIP/RAD17/RFC2-5/9-1-1/TopBP1 complex (RAD17-RFC2-RFC3-RFC4-RFC5-RPA1-RPA2-RAD9A-RAD1-HUS1-ATR-ATRIP-TOPBP1) (modification, collaborate)
  Sivasubramaniam et al., Genes Dev 2008
  Evidence: mutant phenotype, assay, physical interaction
• Reactome Reaction: RAD9A → RAD17 (reaction) Hang et al., Genomics 2000, Bermudez et al., Proc Natl Acad Sci U S A 2003, Hopkins et al., Cancer Res 2003, Zou et al., Proc Natl Acad Sci U S A 2003, Ellison et al., PLoS Biol 2003, Lieberman et al., Proc Natl Acad Sci U S A 1996
• Reactome Reaction: RAD9A → RAD17 (indirect_complex) Hang et al., Genomics 2000, Bermudez et al., Proc Natl Acad Sci U S A 2003, Hopkins et al., Cancer Res 2003, Zou et al., Proc Natl Acad Sci U S A 2003, Ellison et al., PLoS Biol 2003, Lieberman et al., Proc Natl Acad Sci U S A 1996

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: RAD9A — RAD17 (physical association, affinity chromatography technology) Zhang et al., EMBO J 2010*
• IRef Biogrid Interaction: RAD9A — RAD17 (physical association, affinity chromatography technology) Dufault et al., Genomics 2003*
• IRef Biogrid Interaction: RAD9A — RAD17 (association, biochemical) Bermudez et al., Proc Natl Acad Sci U S A 2003
• IRef Biogrid Interaction: RAD9A — RAD17 (physical association, affinity chromatography technology) Bermudez et al., Proc Natl Acad Sci U S A 2003
• IRef Biogrid Interaction: RAD9A — RAD17 (direct interaction, pull down) Bermudez et al., Proc Natl Acad Sci U S A 2003
• IRef Biogrid Interaction: RAD9A — RAD17 (physical association, affinity chromatography technology) Rauen et al., J Biol Chem 2000*
• IRef Biogrid Interaction: RAD9A — RAD17 (physical association, affinity chromatography technology) Lindsey-Boltz et al., Proc Natl Acad Sci U S A 2001
• MIPS CORUM Checkpoint Rad complex: Checkpoint Rad complex complex (HUS1-RAD1-RAD17-RAD9A-RFC2-RFC3-RFC4-RFC5) Lindsey-Boltz et al., Proc Natl Acad Sci U S A 2001
• MIPS CORUM RAD17-RFC-9-1-1 checkpoint supercomplex: RAD17-RFC-9-1-1 checkpoint supercomplex complex (HUS1-RAD1-RAD17-RAD9A-RFC2-RFC3-RFC4-RFC5) Bermudez et al., Proc Natl Acad Sci U S A 2003
• IRef Corum Interaction: Complex of 41 proteins (association, molecular sieving) Lindsey-Boltz et al., Proc Natl Acad Sci U S A 2001
• IRef Hprd Interaction: Complex of 65 proteins (in vivo) Griffith et al., J Biol Chem 2002
• IRef Hprd Interaction: RAD9A — RAD17 (in vivo) Rauen et al., J Biol Chem 2000*, Bermudez et al., Proc Natl Acad Sci U S A 2003
• IRef Hprd Interaction: RAD9A — RAD17 (in vitro) Rauen et al., J Biol Chem 2000*, Bermudez et al., Proc Natl Acad Sci U S A 2003
• IRef Intact Interaction: RAD17 — RAD9A (physical association, anti bait coimmunoprecipitation) Zhang et al., EMBO J 2010*
• IRef Ophid Interaction: RAD17 — RAD9A (aggregation, confirmational text mining) Rauen et al., J Biol Chem 2000*
• IRef Ophid Interaction: RAD17 — RAD9A (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Janes et al., J Cell Sci 2012 : At the DNA, Rad9 activates the checkpoint kinases Rad3 ( ATR ) and Chk1 to arrest cells in G2
Weinert et al., Genetics 1993 : First, the four cdc RAD mutants that required RAD9 each arrested in the late S/G2 phase after a shift to the restrictive temperature when DNA replication was complete or nearly complete, and second, each leaves DNA lesions when the CDC gene product is limiting for cell division
Paulovich et al., Genetics 1998 : We find that RAD9, RAD17, RAD24 , and MEC3 are required for UV-induced ( although not spontaneous ) mutagenesis, and that RAD9 and RAD17 ( but not REV3, RAD24, and MEC3 ) are required for maximal induction of replication dependent sister chromatid exchange ... We find that RAD9 , RAD17, RAD24, and MEC3 are required for UV-induced ( although not spontaneous ) mutagenesis, and that RAD9 and RAD17 ( but not REV3, RAD24, and MEC3 ) are required for maximal induction of replication dependent sister chromatid exchange