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IL6 — RAG1

Text-mined interactions from Literome

Hillion et al., Autoimmun Rev 2007 (Autoimmune Diseases) : Peripheral expression of RAG in human B lymphocytes in normal and pathological conditions is dependent on interleukin-6
Rochas et al., Arthritis Rheum 2009 (Arthritis, Rheumatoid...) : Transmembrane BAFF from rheumatoid synoviocytes requires interleukin-6 to induce the expression of recombination activating gene in B lymphocytes
Yan et al., J Autoimmun 2012 : Diminishing IL-6 by blocking antibody or haplo-insufficiency leads to reduced expression of the IL-7 receptor and RAG and increased titers of anti-DNA antibodies following immunization with a peptide mimetope of DNA
Tagoh et al., Blood 1996 : Among recombinant cytokines, interleukin-3 (IL-3), IL-6, and IL-7, but not IL-2, IL-4, stem cell factor (SCF), and granulocyte-macrophage colony stimulating factor ( GM-CSF ) could induce RAG-1 activation in FL8.2.4.4 cells, and a significant synergistic effect between IL-3, IL-6, and IL-7 was observed
Muraguchi et al., Leukemia & lymphoma 1998 : Among the cytokines, IL-3, IL-6 , and IL-7, but not IL-2, IL-4, SCF, GM-CSF induces RAG activation